Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6034172 | NeuroImage | 2011 | 11 Pages |
Abstract
⺠Multicenter multimodality (DTI and PET) longitudinal study. ⺠Identification of sensitive biomarkers associated with early disease status. ⺠HD related shift in maturation and ageing in TgHD versus the Wt animals. ⺠Suggestive for an early developmental origin of the disease. ⺠Mutant huntingtin interferes with brain development.
Keywords
Corpus callosumhttDTIaxial diffusivityMRIradial diffusivityRapid Acquisition with Relaxation EnhancementHuntington's diseasediffusion tensor imagingMagnetic resonance imagingNeuroimagingPositron emission tomographymean diffusivityTransgenic rat modelRAREfractional anisotropywild-typeHuntingtinPETbinding potentialGlobus pallidus
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Authors
Ines Blockx, Nadja Van Camp, Marleen Verhoye, Raphael Boisgard, Albertine Dubois, Benoit Jego, Elisabeth Jonckers, Kerstin Raber, Karine Siquier, Bertrand Kuhnast, Frédéric Dollé, Huu Phuc Nguyen, Stephan Von Hörsten, Bertrand Tavitian,