| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6035979 | NeuroImage | 2011 | 6 Pages |
Abstract
⺠First longitudinal study of disease progression in extrastriatal areas in PD. ⺠Loss of extrastriatal monoamine neurons occurs later than nigrostriatal degeneration. ⺠Brain compensatory adaptive mechanisms are lost within first few years of disease. ⺠Hypothalamus targeted at early stages of the disease with a fast progression rate. ⺠18F-dopa PET can be used to assess disease progression in extrastriatal areas.
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Authors
Nicola Pavese, Maria Rivero-Bosch, Stephanie J. Lewis, Alan L. Whone, David J. Brooks,