Novel Fast Marching for Automated Segmentation of the Hippocampus (FMASH): Method and validation on clinical data

► Evaluation of this novel hippocampal segmentation method on two clinical datasets. ► Fully-automated initialization of the propagating front using local means analysis. ► A novel input potential combines intensity features and a hippocampal spatial prior. ► A robust and accurate stopping criterion is established. ► Accurate, consistent segmentation performance compared to other established methods.