| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6036239 | NeuroImage | 2011 | 9 Pages |
Abstract
⺠We detect widespread white matter diffusivity changes in early multiple sclerosis. ⺠Higher diffusivity in motor pathways correlate with impaired fine motor skills. ⺠Increased callosal motor fiber radial diffusivity predicts declining hand function. ⺠Diffusivity predicts motor status better than global or tract-specific lesion volume. ⺠Diffusion changes in relevant pathways are promising biomarkers for MS progression.
Keywords
NHPTTBSSMSFCDTIPASATRRMsEDSSCStaxial diffusivityrelapsing remitting multiple sclerosistract-based spatial statisticsFLAIRradial diffusivityfluid attenuated inversion recoverydiffusion tensor imagingcorticospinal tractMultiple sclerosisfractional anisotropyNine Hole Peg TestMultiple sclerosis functional composite
Related Topics
Life Sciences
Neuroscience
Cognitive Neuroscience
Authors
Kyle C. Kern, Joseph Sarcona, Michael Montag, Barbara S. Giesser, Nancy L. Sicotte,