| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6041643 | Neuromuscular Disorders | 2013 | 4 Pages |
Abstract
Three very elderly (over 80Â years old) patients having generalized myasthenia gravis without thymoma were treated with cyclosporin A and followed for up to 24Â months. Cyclosporin A therapy quickly improved myasthenia gravis symptoms in all cases, which allowed a rapid reduction in the prednisolone dose and improvement of prednisolone-related hyperglycemia and hypertension. Combination therapy with prednisolone and low-dose cyclosporin A not only improved the clinical symptoms of the very elderly myasthenia gravis patients but also resulted in a rapid reduction in prednisolone dosage and prednisolone-related side effects. Attention should be paid to cyclosporin A-related renal dysfunction.
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Authors
Seika Nakamura, Satoshi Kaneko, Akiyo Shinde, Jun-ichi Morita, Kengo Fujita, Satoshi Nakano, Hirofumi Kusaka,