Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6042892 | Sleep Medicine Reviews | 2014 | 9 Pages |
Abstract
Several studies have shown that ghrelin administration promotes wakefulness in rodents, while in human males it induces sleep but has no effect in women. Ghrelin also plays an important role in metabolism and appetite regulation, and as described in this review may participate in the energy balance during sleep. In this review, we summarize some of the effects induced by ghrelin administration on the sleep-wake cycle in relation to the effects of other hormones, such as growth hormone, leptin, and orexin. Finally we discuss the relationship between sleep deprivation, obesity and ghrelin secretion pattern.
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Fabio GarcÃa-GarcÃa, Enrique Juárez-Aguilar, Juan Santiago-GarcÃa, Daniel P. Cardinali,