| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6045457 | World Neurosurgery | 2015 | 6 Pages |
Abstract
Deletion of the chromosome 21 allele may be associated with tumorigenesis of meningioma in Down syndrome. This supports the hypothesis that some genes whose expression is increased on the extra copy of chromosome 21 function as tumor suppressor genes and that they contribute to the reduced tumor incidence in individuals with Down syndrome.
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Neuroscience
Neurology
Authors
Takahiro Yamamoto, Naoki Shinojima, Tatemi Todaka, Shigeyuki Nishikawa, Shigetoshi Yano, Jun-ichi Kuratsu,