Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6050743 | Archives of Oral Biology | 2016 | 48 Pages |
Abstract
We demonstrate an inexpensive, efficient, highly reproducible and non-invasive model of mouse TMJ OA. The mechanical nature of the malocclusion resembles the natural development of TMJ OA in humans, making this an ideal model in future studies that aim to elucidate the pathogenesis of the disease leading to the discovery of a treatment. The RAGE plays a role in mouse TMJ OA.
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Authors
E.M.Chávez MatÃas, D.K. Mecham, C.S. Black, J.W. Graf, S.D. Steel, S.K. Wilhelm, K.M. Andersen, J.A. Mitchell, J.R. Macdonald, W.R. Hollis, D.L. Eggett, P.R. Reynolds, D.L. Kooyman,