| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6050779 | Archives of Oral Biology | 2016 | 23 Pages |
Abstract
The regulation of the prenylated protein RHOB in this study was consistent with the known effects of zoledronic acid on the mevalonate pathway. The down regulation of CCL2 and IL6 and the upregulation of CD55 may be associated with suppression of inflammation. An increase in VEGFA and BMP2 gene expression suggests that fibroblasts respond to zoledronic acid by producing a proangiogenic environment.
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Authors
E.J. Ohlrich, D.E. Coates, M.P. Cullinan, T.J. Milne, S. Zafar, Y. Zhao, W.D. Duncan, G.J. Seymour,