Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6050901 | Archives of Oral Biology | 2015 | 9 Pages |
Abstract
We conclude that smoking may induce changes in DNA methylation status in cancer-related genes of oral epithelial cells and that the cessation of smoking is capable of reversing this process. Based on our data, we suggest that DNA methylation status of the hTERT and MLH1 gene promoters are promising markers for screening a set of smoking-related alterations in oral cells.
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Authors
Sabrina Rocha Luna De Oliveira, Isabelle Cristina Borba Da Silva, Bruno Augusto Linhares Almeida Mariz, Ana Maria Barros Chaves Pereira, Naila Francis Paulo De Oliveira,