| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6051170 | Archives of Oral Biology | 2012 | 8 Pages |
Abstract
It is proposed that PGE2at a low dose switch osteoblast's biology in favour of bone apposition by: first, inducing a significantly higher OPG gene expression overwhelming RANKL gene expression; second, reducing PGEs synthesis; and third, increasing ALP gene expression. An opposite effect is expected when the concentration of the eicosanoid overpass certain levels.
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Authors
G.O. Ramirez-Yanez, A.L. Symons,