| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6051456 | Archives of Oral Biology | 2011 | 9 Pages |
Abstract
⺠We evaluated the role of PGE2 induced by compressive stress (CS) and tensile stress (TS) on cementoblast metabolism in vitro. ⺠CS and TS enhanced COX-2 mRNA expression and PGE2 production. ⺠Genes related to mineral metabolism were also enhanced by mechanical stimulation on an endogenous PGE2-mediated manner. ⺠It is shown that PGE2 plays an important role on mediating cementoblast mechanosensitivity.
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Authors
Emanuel Braga Rego, Toshihiro Inubushi, Aki Kawazoe, Mutsumi Miyauchi, Eiji Tanaka, Takashi Takata, Kazuo Tanne,