Article ID Journal Published Year Pages File Type
6052076 Archives of Oral Biology 2011 9 Pages PDF
Abstract
Notch signalling plays a crucial role in regulating self-renewal and differentiation in DPSCs. The deficient Notch signalling inhibits the self-renewal capacity of DPSCs and tends to induce DPSCs differentiation under odontoblast differentiation-inducing conditions. These findings suggested that DPSCs/Delta1-RNAi might be applicable to stem cell therapies and tooth tissue engineering.
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Related Topics
Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine
Preview
Inhibition of Delta1 promotes differentiation of odontoblasts and inhibits proliferation of human dental pulp stem cell in vitro
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