Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6052080 | Archives of Oral Biology | 2011 | 8 Pages |
Abstract
Together, our results demonstrate that hLF1-11 and P-113 display antibacterial activity against dental cavity-inducing S. mutans through an intracellular mechanism that could involve DNA binding. Thus, these peptides might be attractive and valuable candidates for development into effective antimicrobial therapies to combat dental caries.
Keywords
CFUMICShLFAMPsBHICalcein-AMHSTS. mutansHistatinsFITCC. albicansS. gordoniiArginineElectrophoretic mobility shift assayDNA bindingArgMRSAmethicillin-resistant Staphylococcus aureusStreptococcus sanguisStreptococcus mutansStreptococcus gordoniiMinimal inhibitory concentrationsEMSA یا electrophoretic mobility shift assay brain heart infusion brothfluorescein isothiocyanateLactoferrinHuman lactoferrinSEMScanning electron microscopyHistatin 5colony-forming unitAntimicrobial peptidesCandida albicanscalcein acetoxymethyl ester
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Authors
Lijun Huo, Kai Zhang, Junqi Ling, Zhixiang Peng, Xiangya Huang, Hongyan Liu, Lisha Gu,