Extracts of irradiated mature human tooth crowns contain MMP-20 protein and activity

Article ID	Journal	Published Year	Pages	File Type
6053799	Journal of Dentistry	2014	10 Pages	PDF

Abstract

MMP-20 is a radiation-resistant component of mature tooth crowns enriched in the dentine-enamel. We speculate that MMP-20 catalyzed degradation of organic matrix at this site could lead to enamel delamination associated with oral cancer radiotherapy.

Keywords

buffer B MMP PBS SDS Mmp-20 PTO 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate BSA bovine serum albumin EDTA ethylene diaminetetraacetic acid Acetic acid HAC buffer A Gray DEJ Radiotherapy sodium dodecyl sulfate Oral cancer Mass spectrometry Phosphate buffered saline matrix metalloproteinase Matrix metalloproteinase-20 CHAPS

Related Topics

Health Sciences Medicine and Dentistry Dentistry, Oral Surgery and Medicine

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Extracts of irradiated mature human tooth crowns contain MMP-20 protein and activity

Authors

J.D. McGuire, A.A. Mousa, Bo. J. Zhang, L.S. Todoki, N.T. Huffman, K.B. Chandrababu, J. Moradian-Oldak, A. Keightley, Y. Wang, M.P. Walker, J.P. Gorski,