Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6054928 | Oral Oncology | 2015 | 4 Pages |
Abstract
Targeted immunotherapy promoting anti-tumor T-cell activity has shown improved survival and durable objective responses in advanced melanoma patients. Data is mounting that concurrent use of ipilimumab and nivolumab has a more pronounced effect than either as monotherapy. Although no completed clinical trials exist for their use in head and neck cancer, preclinical data suggests these therapies would be beneficial in head and neck malignancies as well. Their role in head and neck cancer management is an ongoing research effort.
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Authors
Mark S. Swanson, Uttam K. Sinha,