Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6054986 | Oral Oncology | 2014 | 7 Pages |
Abstract
Promoter methylation profiling of LSCC using MS-MLPA identified CDKN2B, DAPK1, RARβ, APC, and CHFR as frequent epigenetic events. The clinical implications of these genes as biomarkers are highly relevant as attractive targets for cancer therapy, given the reversible nature of epigenetic gene silencing.
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Authors
Fernando López, Teresa Sampedro, José L. Llorente, Francisco DomÃnguez, Mario Hermsen, Carlos Suárez, César Álvarez-Marcos,