Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6056713 | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | 2015 | 6 Pages |
ObjectiveTo compare measures of dry mouth following extended use of an alcohol-based mouthrinse (LISTERINE Antiseptic [LA]) and a non-alcohol-based mouthrinse (Crest Pro-Health Rinse [CPH]) on healthy adults with “normal” salivary flow.MethodsThis single-site, randomized, observer-blinded, parallel study compared unstimulated whole salivary flow and perceived dryness following daily use at weeks 4 and 12 versus baseline. Noninferiority, between-treatment flow comparisons (0.15Â mL/min margin), and between-treatment comparisons of the mean Bluestone Mouthfeel Questionnaire (BMQ) visual analog scale scores were made using analysis of covariance.ResultsMeasures of dry mouth were comparable between mouthrinses, as demonstrated by both noninferiority of LA versus CPH flow (PÂ <Â .001) and no significant differences between groups in the BMQ measures at 4 or 12Â weeks.ConclusionsExtended use of an alcohol-based mouthrinse is no more likely to cause reduction in salivary flow or perceived dryness in individuals with normal salivary flow compared with a non-alcohol-based mouthrinse (CPH).