Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6056715 | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | 2015 | 15 Pages |
Abstract
A total of 21 studies met the inclusion criteria. This review showed that the use of statins reduced significantly alveolar bone resorption observed during periodontal disease and after tooth extraction. Oral administration was effective using high statin concentrations, although local administration using a biodegradable carrier was effective with lower concentrations. It was recently reported that statins were effective to reduce alveolar bone loss as an adjunct to scaling and root planing (SRP) in several clinical trials. Further studies are needed to confirm these promising results.
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Authors
Erwan MD, Silke PhD, Sylvain DDS, PhD, Jean-Christophe DDS, PhD,