Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6056909 | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | 2014 | 10 Pages |
ObjectiveThis study describes the occurrence of histopathologic characteristics of oral lichenoid mucositis in epithelial dysplasia and squamous cell carcinoma.Study DesignThis retrospective review examined 352 histologic specimens of group 1 (mild to moderate dysplasia), group 2 (severe dysplasia or carcinoma in situ), and group 3 (squamous cell carcinoma) for correlation between 5 histologic characteristics frequently found in oral lichen planus and grade, age, gender, and oral subsite.ResultsIn this sample, 29% of all cases exhibited 3 or more lichenoid features. Lichenoid features were significantly more frequent in group 1 over group 2 lesions for cases meeting a minimum lichenoid threshold (PÂ = .001). No statistically significant patterns were noted for age or gender. The buccal mucosa was significantly overrepresented (PÂ = .039) and the floor of the mouth was significantly underrepresented (PÂ = .049) in regard to lichenoid feature frequency.ConclusionsThis study confirms the frequent correlation of lichenoid characteristics in oral premalignant and malignant lesions.