Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6057746 | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology | 2013 | 7 Pages |
ObjectivesTo examine the histopathological characteristics of inflammatory lesions containing Actinomyces based on DNA sequencing. Furthermore, case reports of actinomycosis in the maxillofacial region are summarized by a review of the literature.Study designThe study comprised 12 cases of inflammatory lesions containing Actinomyces as diagnosed by DNA analysis. The average age of the subjects was 59 ± 15 years (6 males; 6 females).ResultsThe distribution of causative bacteria was: Actinomyces israelii in 9 cases, Actinomyces gerencseriae in 2 cases, and Actinomyces naeslundii in 1 case. Four cases diagnosed by DNA sequencing were positive for “Druse,” a known morphological diagnostic characteristic of actinomycosis, and 8 cases lacked typical colony formation.ConclusionsDNA analysis using paraffin-embedded samples is effective for both early and accurate diagnosis of oral lesions containing Actinomyces.