Peripheral nerve function in patients with excessive fragmentary myoclonus during sleep

The high prevalence of abnormal neurophysiological findings in patients with excessive fragmentary myoclonus during polysomnography suggests that excessive fragmentary myoclonus during sleep according to AASM criteria is not primarily a sleep-related phenomenon, but only persists during sleep and points to peripheral nerve pathology at least in part of the cases. Patients with incidental EFM during polysomnography should undergo electrophysiological workup for peripheral nerve pathology.