| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6060942 | Sleep Medicine | 2015 | 11 Pages |
Abstract
The majority of studies that performed explored blood-based biomarkers, with most not identifying definitive morbidity biomarkers. Of the potentially promising morbidity biomarkers, plasma IL-6 and high sensitivity C-reactive protein appear to exhibit a favorable profile, and may discriminate OSA patients with and without morbidities in both adults and children. MRP 8/14 was retained in children as well as cardiovascular morbidity-associated biomarker. Urinary neurotransmitters may also provide a good tool for screening OSA cognitive morbidity in children.
Keywords
IL-6MRPaHIIGFEDSOAIhsCRPROCDTAAASMEBCRDISleep apneaobstructive sleep apneaAmerican Academy of Sleep Medicineinterleukin-6Osacardiovascular diseaseexcessive daytime sleepinessdiagnostic test accuracyCVDApnea hypopnea indexRespiratory disturbance indexMorbidityInsulin-like growth factorExhaled breath condensateReviewRisk ratioodds ratioBiomarkersPSGmyeloid-related proteinhigh-sensitivity C-reactive proteinPolysomnographyreceiver operating characteristic
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Authors
Graziela De Luca Canto, Camila Pachêco-Pereira, Secil Aydinoz, Paul W. Major, Carlos Flores-Mir, David Gozal,