Association analysis of the major histocompatibility complex, class II, DQ β1 gene, HLA-DQB1, with narcolepsy in Han Chinese patients from Taiwan

Our data add further support to the strong association of the HLA-DQB1∗06:02 allele with narcolepsy, especially in narcolepsy + cataplexy patients. Our study also indicates additional HLA-DQB1 alleles may modify the presentation of narcolepsy + cataplexy patients, such as DQB1∗03:01 and DQB1∗06:01 in our study. Our results are limited by the small sample size and can only be considered as preliminary findings.