House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs

Article ID	Journal	Published Year	Pages	File Type
6062279	Journal of Allergy and Clinical Immunology	2016	14 Pages	PDF

Keywords

NU7441 HDM 8-OHdG H2AX DCFH-DA SSB BAL EPO NHEJ BEAS-2B 3-NT histone 2Ax 8-oxoG AHR DSB CC10 DNAPK 2,7-dichlorodihydrofluorescein diacetate 3-nitrotyrosine 8-oxoguanine 8-Hydroxy-2-deoxyguanosine ataxia-telangiectasia mutated MPO DMSO DNA double-strand breaks ROS Asthma eosinophil peroxidase DNA repair Oxidative stress Par ATM Dimethyl sulfoxide RONS double-strand break single-strand break bronchoalveolar lavage Cell death myeloperoxidase Homologous recombination DNA-dependent protein kinase catalytic subunit DNA-dependent protein kinase Airway hyperresponsiveness Propidium iodide Nonhomologous end-joining House dust mite Reactive oxygen and nitrogen species Reactive oxygen species

Related Topics

Life Sciences Immunology and Microbiology Immunology

House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs

Authors

Tze Khee BSc, Xin Yi BSc, Hong Yong BSc, W.N. Felicia BSc, W.S. Daniel BSc, Na PhD, Ian J.J. BEng, W.S. Fred PhD, Bevin P. ScD,