Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062294 | Journal of Allergy and Clinical Immunology | 2016 | 8 Pages |
Abstract
These data demonstrate a rate of cross-reactivity between aminopenicillins and aminocephalosporins (ie, cephalexin, cefaclor, and cefadroxil) of around 20%, as well as the absence of cross-reactivity between penicillins and cefuroxime, ceftriaxone, and aztreonam in all subjects with TÂ cell-mediated hypersensitivity to penicillins, almost exclusively aminopenicillins. Therefore these subjects could be treated with cefuroxime, ceftriaxone, and aztreonam. In those who especially require cephalosporin or aztreonam treatment, however, we recommend pretreatment skin tests because negative responses indicate tolerability.
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Authors
Antonino MD, Francesco MD, Rocco Luigi MD, Michela MD, Cristiano MD, Donato MD,