| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6062372 | Journal of Allergy and Clinical Immunology | 2016 | 28 Pages |
Abstract
None of the patients with negative SPT and ICT results for rhC1INH had allergic symptoms during rhC1INH challenge. The negative predictive value of the combination of SPT and ICT for the outcome of the SC challenge was 100% (95% CI, 84.6%-100%). SC administration of rhC1INH was well tolerated.
Keywords
CMAC1INHBATSPTC1 esterase inhibitorSpecific IgETEAEintracutaneous testBasophil activation testAllergenicitycow's milk allergyHereditary angioedemanegative predictive valueSubcutaneous administrationSkin prick testIntradermal testingsubcutaneousadverse eventtreatment-emergent adverse eventICTNPV یا negative predictive valuesIgE
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Authors
Mignon T. MD, Harmieke PhD, Heike MD, PhD, Els PhD, Ans F.M. BSc, Helma BAS, Rob J.B. MD, PhD, Carla A.F.M. MD, PhD, C. Erik PhD, Leonard PhD, Anurag MD, André C. MD, PhD,