Article ID Journal Published Year Pages File Type
6062377 Journal of Allergy and Clinical Immunology 2016 33 Pages PDF
Abstract
The pruritus- and TH2-associated novel cytokine IL-31 induces a distinct transcriptional program in sensory neurons, leading to nerve elongation and branching both in vitro and in vivo. This finding might help us understand the clinical observation that patients with atopic dermatitis experience increased sensitivity to minimal stimuli inducing sustained itch.
Related Topics
Life Sciences Immunology and Microbiology Immunology
Authors
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