Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062601 | Journal of Allergy and Clinical Immunology | 2016 | 19 Pages |
Abstract
Petrolatum robustly modulates antimicrobials and epidermal differentiation barrier measures. These data shed light on the beneficial molecular responses of petrolatum in barrier-defective states, such as AD and postoperative wound care.
Keywords
hBD2human β-defensin 2FLGLCN2PI3FCHTEWLACDAHRAMPH&ELORTransepidermal water lossOcclusionInnate immunityIHCImmunohistochemistryPatch testsfold changeAtopic dermatitisACD, Allergic contact dermatitisDendritic cellDEGfilaggrinStratum corneumLoricrinLipocalin 2BarrierMoisturizerHematoxylin and EosinpetrolatumAntimicrobial peptideAntimicrobial peptidesDifferentially expressed genequality controlaryl hydrocarbon receptor
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Authors
Tali MD, Dana BA, Saakshi MD, Joel PhD, Riana ScB, Robert MD, Nikhil MD, Peng MSc, Hui MSc, Yeriel D. BS, Xiuzhong MSc, Patricia NP, Mary NP, Mayte PhD, Avner MD, James G. MD, PhD, Emma MD, PhD,