Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062627 | Journal of Allergy and Clinical Immunology | 2016 | 10 Pages |
Abstract
This work emphasizes the utility of whole-genome analyses combined with immunologic investigation in patients with unresolved immunodeficiency. This approach is likely to provide an insight into immunologic pathways and mechanisms of disease. It also provides molecular evidence for more targeted therapies. In addition, our report further corroborates a potential role of ADA2 in modulating immunity and inflammation.
Keywords
CECR1panarteritis nodosaAdenosine deaminase 2Array-CGHIL-17RAOMIMPFAPAAPCESRadenosine deaminaseallophycocyaninChronic inflammationvasculitiserythrocyte sedimentation ratefluorescence in situ hybridizationFishPANArray-based comparative genomic hybridizationADAOnline Mendelian Inheritance in Manchronic mucocutaneous candidiasisImmunodeficiency
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Authors
Florence MD, PhD, Federica MD, PhD, Jacqueline MD, Matthieu PhD, Natalia Arenas Ramirez, Gregoire MSc, Onur MD, Olivier PhD, Stephanie MD, Daniel MD, Marco PhD, Annette MD, Michel MD, Pierre-Yves MD, Yannick MD, Maya MD, Pierre-Alexandre MD,