Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062630 | Journal of Allergy and Clinical Immunology | 2016 | 9 Pages |
Abstract
ITK and BTK regulate thermal homeostasis during septic response through mast cell function in mice. They share regulatory function downstream of Toll-like receptor 4/LPS in mast cells, through regulating the activation of canonical nuclear factor kappa B, phosphatidylinositol-4,5-bisphosphate 3-kinase/Akt, and p38 signaling pathways.
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Authors
Weishan PhD, J. Luis PhD, Victor P. BS, Avery PhD,