Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062753 | Journal of Allergy and Clinical Immunology | 2016 | 21 Pages |
Abstract
peTH2 cells are the primary functional proinflammatory human TH2 cell subpopulation underlying allergic eosinophilic inflammation. The unambiguous phenotypic identification of human peTH2 cells provides a powerful tool to track these cells in future pathogenesis studies and clinical trials.
Keywords
CD4Mucosal-associated invariant THPGDSEGIDCD161CD62 ligandCD62LChemoattractant receptor–homologous molecule expressed on TH2 cellsTh2Eosinophilic gastrointestinal diseaseTSLPPGD2phorbol 12-myristate 13-acetateHDMIL-5ILC2CRTH2CLAPMAcutaneous lymphocyte-associated antigenEosinophilic inflammationAtopic dermatitisphycoerythrinThymic stromal lymphopoietinMAITtype 2 innate lymphoid cellhematopoietic prostaglandin D synthaseProstaglandin D2House dust mite
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Authors
Alyssa BS, Yuzhi MD, PhD, Daniel L. PhD, Michael RN, Hyejeong RN, Sarah RN, Nancy MD, Christopher MD, Joshua D. MD, Kelly D. MD, PhD, Stephen A. MD, Calman MD,