Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062861 | Journal of Allergy and Clinical Immunology | 2016 | 11 Pages |
Abstract
This study represents the first example that underscores the remarkable potential of SIgA to serve as a carrier for a protein antigen in a mucosal vaccine approach targeting the nasal environment.
Keywords
MIPUlex europaeus agglutinin 1Dendritic cell–specific intercellular adhesion molecule 3–grabbing nonintegrinUEA-1microfold cellsMicrofold cellDC-SIGNMCP-1PLAHLTNALTsIgANasal-associated lymphoid tissuesecretory componentSecretory IgAheat-labile toxinProtectionDendritic cellknockoutmonocyte chemoattractant protein 1macrophage inflammatory proteinPolylactic acid
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Authors
Nicolas PhD, Vincent PhD, Bernard PhD, Fabienne Jospin, Agathe Ensinas, Christian MD, Blaise PhD, Stéphane PhD,