| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6062947 | Journal of Allergy and Clinical Immunology | 2016 | 11 Pages |
Abstract
IL-25 and IL-33 can interact locally with IL-17RB+ST2+ polyp T cells to augment TH2 responses in patients with CRSwNP. A local TH17 response might be important in healthy nasal mucosal immune homeostasis.
Keywords
IL-33T-cell phenotypeCRSwNPCDR3AIM2IL-17RBIL-25Th17 cellsILC2CRTH2ST2MicroarrayChronic rhinosinusitis with nasal polypsChronic rhinosinusitis with nasal polyposisTH2 cellsnasal mucosaComplementarity-determining region 3chemoattractant receptor-homologous molecule expressed on Th2 cellstype 2 innate lymphoid cellabsent in melanoma 2
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Authors
Emily P.S. PhD, Harsha H. FRCP, PhD, Batika M.J. PhD, Stephen R. MD, FRCP, Andrew N.J. PhD, Nicholas MRCP, PhD, Nara MD, Melissa MSc, Claire FRCS (ORL-HNS), Sun MD, PhD, Joanne FRCS (ORL-HNS), Valerie J. MD, FRCS, David J. PhD, Stephen J. FRCP, PhD,