Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6062951 | Journal of Allergy and Clinical Immunology | 2016 | 9 Pages |
Abstract
Our results demonstrate that the proximity of IgE epitopes on an allergen affects its allergenic activity. We thus identified a novel mechanism by which IgE-allergen complexes regulate allergic inflammation. This mechanism should be important for allergy and other immune complex-mediated diseases.
Keywords
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Immunology
Authors
Anna PhD, Birgit PhD, Kenneth H. PhD, Moumita PhD, Marat PhD, Domen PhD, Clarissa R. PhD, Christian MD, Milena MSc, Margarete PhD, Walter PhD, Fred D. MD, Rudolf MD,