| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6062953 | Journal of Allergy and Clinical Immunology | 2016 | 18 Pages |
Abstract
This study provides evidence for the existence of different transitional B-cell subsets, each displaying unique phenotypic and regulatory functional profiles. Furthermore, the study indicates that altered distribution of transitional B-cell subsets highlights different regulatory defects in patients with different autoimmune diseases.
Keywords
MFIPC5phospholipase Cγ2Transitional B cellsSPADEPLCγ2regulatory BMNCAPCFITCPSSBCRallophycocyaninBregChronic inflammatory diseasesautoimmunitymononuclear cellprimary Sjogren syndromephycoerythrinfluorescein isothiocyanateSystemic lupus erythematosusSLEImmune regulationHealthy control subjectmean fluorescence intensityType 1Type 2Type 3FlockB-cell receptor
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Authors
Quentin MSc, Jacques-Olivier DDS, PhD, Divi MD, Laëtitia PhD, Rizgar A. PhD, FRCP, FRCPath, Sophie PhD,