Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6063021 | Journal of Allergy and Clinical Immunology | 2015 | 18 Pages |
Abstract
Our data demonstrate an essential role for IL-10 in inducing an immunoregulatory phenotype in B cells that exerts substantial anti-inflammatory and immunosuppressive functions.
Keywords
SOCSIRF-4XBP-1BR1BLIMP-1GARPMDDCIL-1RATLRAPCMIPPD-L1FITCIL-1 receptor antagonistantigen-presenting cellAnti-inflammatory effectstetanus toxoidToll-like receptorsuppressor of cytokine signalingDendritic cellregulatory B cellsMonocyte-derived dendritic cellInterferon regulatory factor 4granulocyte colony-stimulating factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)G-CSFphycoerythrinfluorescein isothiocyanateToll-like receptor ligandProgrammed cell death 1 ligand 1Immune regulationX-box binding protein 1macrophage inflammatory protein
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Authors
Barbara PhD, Willem PhD, Oliver F. MSc, Beate Sci Tec, Hideaki MD, PhD, Stefan Sci Tec, Cezmi A. MD, Mübeccel MD, PhD,