| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6063085 | Journal of Allergy and Clinical Immunology | 2014 | 10 Pages |
Abstract
Our results demonstrate the utility of eQTL mapping in the identification of novel asthma genes and provide evidence for the importance of FADS2, NAGA, and F13A1 in the pathogenesis of asthma.
Keywords
FADS1qPCRFDRFADS2eQTLcAMPCD4+ lymphocytesQuantitative PCRAsthmaFatty acid desaturase 1fatty acid desaturase 2Polyunsaturated fatty acidPUFANagaFAIREchromatin immunoprecipitationChildhood Asthma Management ProgramExpression quantitative trait locusformaldehyde-assisted isolation of regulatory elementsLinkage disequilibriumGenome-wide association studyGWASfalse discovery rateHaplotypeSingle nucleotide polymorphismSNPCHiPIntegrative genomics
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Authors
Sunita MD, MPH, Xiaobo PhD, Derek M. BS, Blanca E. PhD, Andy MD, Stanley J. MD, Robert MD, Mario MD, Nadia N. PhD, Gregory B. MD, Becky M. PhD, N. Franklin MD, Lydiana MD, Manuel MD, Albino MSc, DrPH, Robert F. MD, Julian MD, Jerry MD, PhD,