Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6063148 | Journal of Allergy and Clinical Immunology | 2015 | 8 Pages |
Abstract
We identified 2 loci associated with exacerbations through a genome-wide association study. CTNNA3 met genome-wide significance thresholds, and SEMA3D replicated in a clinical biobank database.
Keywords
CTNNA3CEBPP2RX7PACTTTNBiobankASMpurinergic receptor P2X, ligand-gated ion channel, 7eQTLICScAMPAsthmaChildhood asthmaCareChildhood Asthma Management ProgramExpression quantitative trait locusChildhood Asthma Research and EducationexacerbationTitinMarsLinkage disequilibriumAirway smooth musclePediatric Asthma Controller TrialGenome-wide association studyGWASCCAAT/enhancer-binding proteinSingle nucleotide polymorphismSNPCLICInhaled corticosteroid
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Michael J. PhD, Ann C. MD, Sze Man MD, George L. MS, Joanne ScD, Blanca E. PhD, Jessica PhD, Robert P. MS, Fernando D. MD, Peter MD, Christian M. BS, Hua PhD, Josh C. MD, Dan M. MD, Reynold A. MD, Benjamin A. MD, Scott T. MD, Kelan G. MD,