Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6063656 | Journal of Allergy and Clinical Immunology | 2016 | 11 Pages |
Abstract
PLZF expression at the innate lymphoid cell precursor stage has a long-range effect on the functional properties of mature ILC2s and highlights the importance of these cells for innate allergic responses in otherwise immunocompetent mice.
Keywords
TCrIL-7 receptor αICOSRAGiNKTPLZFIL-7Rαphorbol 12-myristate 13-acetateILC2DAPICLPILC4′,6-diamidino-2-phenylindolePMApromyelocytic leukemia zinc fingerinnate lymphoid cellInnate lymphoid cellsinvariant natural killer TMouse modelsknockouttype 2 innate lymphoid cellwild-typecommon lymphoid progenitorRecombination-Activating GeneInducible costimulatorT-cell receptor
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Authors
Philip A. MD, PhD, Michael G. PhD, Benjamin D. PhD, Joseph F. PhD, Anne I. PhD, Albert MD, PhD,