| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6063985 | Journal of Allergy and Clinical Immunology | 2014 | 17 Pages |
Abstract
EMR1 expression is restricted to mature blood and tissue eosinophils. Targeting of eosinophils with afucosylated anti-EMR1 antibody shows promise as a treatment for eosinophilic disorders.
Keywords
EGFEmr1EDNIL-5RIL-5 receptorMBPAECPBSTEPXNIHADCCECPnatural killerantibody-dependent cell-mediated cytotoxicityEosinophileosinophil peroxidaseEosinophiliaHESChoChinese Hamster Ovaryabsolute eosinophil countHypereosinophilic syndromeepidermal growth factorNational Institutes of HealthGeometric meanEosinophil-derived neurotoxinmajor basic proteinEosinophil cationic protein
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Authors
Fanny PhD, PharmD, Nenad PhD, Olga PhD, Chyi-Chia Richard MD, PhD, Zengfang PhD, Mark MD, Michelle A. MS, Varghese PhD, John BS, Mark PhD, Geoffrey PhD, Irina MD, Christopher PhD, Amy D. MD,