Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6064100 | Journal of Allergy and Clinical Immunology | 2015 | 20 Pages |
Abstract
FcεRI stimulation of MCs promotes autocrine secretion of HK-1, which signals through NK1R to provide adjuvancy for efficient development of FcεRI-MC-mediated disorders.
Keywords
NF-κBTNFDNP-HSABMMCFcεRIPMNHK-1NK1RGPCRPFABALOVAERKEPOIL-6PI3KIgEJnkPSAc-Jun N-terminal kinaseMPOG protein–coupled receptorPCApassive systemic anaphylaxisPassive cutaneous anaphylaxiseosinophil peroxidaseAirway inflammationOvalbuminBone marrow–derived mast cellnuclear factor κBphosphoinositide 3-kinasebronchoalveolar lavageSubstance PMast cellsMast cellmyeloperoxidasewild-typehemokinin-1paraformaldehydePolymorphonuclearextracellular signal-regulated kinaseNeurokinin-1 receptor
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Authors
Tina L. PhD, Chin H. MD, Anna R. BS, Olga A. BS, William J. BS, Darling M. PhD, Adrian E. MD, PhD, Adriana T. MD, PhD,