| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6064104 | Journal of Allergy and Clinical Immunology | 2015 | 19 Pages |
Abstract
In summary, the data collectively show a role of the contact system in patients with anaphylaxis and support the hypothesis that targeting bradykinin generation and signaling provides a novel and alternative treatment strategy for anaphylactic attacks.
Keywords
IQRPCKFXIIFXIIaC1INHMABPB2RFXIDNP-HSAACEB1RAPTTPRCPKLKB1C1 esterase inhibitorAnaphylaxisHereditary angioedemaAngiotensin-converting enzymebradykinin B2 receptorbradykininTryptaseHAEactivated partial thromboplastin timeContact systemAnti-XaFactor XIFactor XIImean arterial blood pressureMast cellinterquartile rangeMouse modelswild-typeNitric oxideProlylcarboxypeptidaseplasma kallikreinHigh-molecular-weight kininogenbradykinin B1 receptor
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Anna MD, PhD, Jenny MSc, Riccardo MD, Mar MD, PhD, Victoria MD, PhD, Moises MD, PhD, Katrin F. PhD, Lynn PhD, Olga MD, PhD, Parvin MSc, Linda MSc, Andy PhD, Antonio PhD, Ellinor PhD, Anne PhD, Thorsten MD, Hartmut PhD, Tobias PhD, Thomas MD, PhD,