Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6064407 | Journal of Allergy and Clinical Immunology | 2014 | 10 Pages |
Abstract
Our results indicated that downregulated BCL2L10 caused by miR-18a-5p overexpression mediates intrinsic keratinocyte apoptosis in patients with TEN. Serum miR-18a-5p levels can be a useful disease marker for drug eruptions.
Keywords
NHEKSJSBSASmall interfering RNAsiRNAcycle thresholderythema multiformeTerminal deoxynucleotidyl transferase-mediated dUTP nick end labelingTUNELApoptosistenSerumbody surface areaStevens-Johnson syndromedrug eruptionUTR یا untranslated regions untranslated regionMicroRNAMiRNAToxic epidermal necrolysisKeratinocyteNormal human epidermal keratinocyte
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Authors
Asako MD, PhD, Zhongzhi PhD, Masatoshi MD, PhD, Yuki Izuno, Naoki PhD, Keitaro Yamane, Akihiko MD, Chikako MD, PhD, Satoshi MD, PhD, Yuji MD, PhD, Hironobu MD, PhD,