Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6064421 | Journal of Allergy and Clinical Immunology | 2014 | 21 Pages |
Abstract
High-throughput TCR sequencing of rare immune disorders has demonstrated that quantitative TCR diversity can appear normal despite qualitative changes in repertoire and strongly suggests that in human subjects RAG enzymatic function might be necessary for normal CDR3 junctional diversity.
Keywords
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Immunology
Authors
Xiaomin PhD, Jorge R. PhD, Sam PhD, Mirjam PhD, Suk See MD, PhD, Harry MD, Andrew MD, Ivan MD, Mary Louise MD, PhD, Daniel C. MD, PhD, Joshua D. MD,