| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6064441 | Journal of Allergy and Clinical Immunology | 2014 | 18 Pages |
Abstract
PGD2 is an important and potent activator of ILC2s through CRTH2 mediating strong proallergic inflammatory responses. Through IgE-mediated mast cell degranulation, these innate cells can also contribute to adaptive type 2 immunity; thus CRTH2 bridges the innate and adaptive pathways in human ILC2s.
Keywords
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Authors
Luzheng PhD, Maryam MD, Isabel BTA, Jenny M. PhD, Andrew N.J. PhD, Hergen PhD, Paul F Med Sci, Graham DPhil, FRCP,