| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6064768 | Journal of Allergy and Clinical Immunology | 2015 | 11 Pages |
Abstract
FA is associated with the increased presence of eosinophils in the LNs and large airways, which express HLA-DR and costimulatory molecules. The expression of Factor XIIIa+ monocyte-derived DCs, CD4+ and CD8+ T cells, CD20+ B cells, and CD23+ cells was increased in the large airways without a corresponding increase in the expression of these cells in the bronchopulmonary LNs. These findings support the concept that eosinophils might act as antigen-presenting cells in patients with FA.
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Authors
Erika Feltrini PhD, Diogenes Seraphim MD, PhD, Luiz Fernando MD, PhD, Ana Laura PhD, Angela Batista MSc, Maria Cristina BSc, Marisa MD, PhD, Klaus F. MD, PhD, Thais MD, PhD,