Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6064836 | Journal of Allergy and Clinical Immunology | 2014 | 13 Pages |
Abstract
Our findings indicate relevant involvement of at least 3 COPD genes in lung development and lung growth by demonstrating associations pointing toward reduced airway caliber in early childhood. Furthermore, our results suggest that COPD genes are involved in the infant's lung response to smoke exposure in utero and in early life.
Keywords
PIAMAETsFVCRAGEALSPACAvon Longitudinal Study of Parents and ChildrenCOPDChronic obstructive pulmonary diseaseIn utero exposureenvironmental tobacco smokeforced vital capacityodds ratioSingle nucleotide polymorphismPrevention and Incidence of Asthma and Mite AllergySNPKOALAReceptor for advanced glycation end products
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Authors
Marjan MD, PhD, H. Marike PhD, Raquel PhD, Alet H. PhD, Bert PhD, Henriëtte A. PhD, Johan C. MD, PhD, Carel PhD, Monique PhD, John PhD, John MD, Gerard H. MD, PhD, Dirkje S. MD, PhD,