Article ID Journal Published Year Pages File Type
6065222 Journal of Allergy and Clinical Immunology 2013 16 Pages PDF
Abstract
Single-dose intravenous and multiple-dose subcutaneous benralizumab reduced eosinophil counts in airway mucosa/submucosa and sputum and suppressed eosinophil counts in bone marrow and peripheral blood. The safety profile supports further development. Additional studies are needed to assess the clinical benefit in asthmatic patients.
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Life Sciences Immunology and Microbiology Immunology
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