Article ID Journal Published Year Pages File Type
6065258 Journal of Allergy and Clinical Immunology 2013 18 Pages PDF
Abstract
The decrease in tissue inflammation during anti-TNF-α therapy is not due to immediate killing of TNF-α-producing cells but rather results from a rapid downregulation of the pathogenic IL-12/IL-23-driven immune response.
Keywords
Related Topics
Life Sciences Immunology and Microbiology Immunology
Preview
Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages
Authors
, , , , , ,